董自梅

1992年毕业于动物学专业，获学士学位，2011年获生命科学学院动物学专业博士学位。长期从事动物资源保护与利用及神经再生机制的研究，主持国家自然科学基金面上项目3项，主持完成河南省重点科技攻关项目1项，河南省自然科学基金项目2项，河南省教学改革项目1项；参与国家自然科学基金面上项目3项，河南重大公益项目1项。河南省高等学校创新团队主持人。在国内外重要学术期刊发表论文60多篇，获得国家教学成果二等奖1项，河南省高等教育教学成果一等奖1项，获河南省自然科学优秀论文一等奖3项。参编的《普通动物学》、《动物学实验技术》2部教材被评为省级规划教材。主讲《普通动物学》、《医学寄生虫学》、《分子生态学》和《动物发育及再生生物学》等本科及研究生课程。

    动物资源保护与利用；组织再生机制研究。

   全国动物学名词审定委员会委员；《中国大百科全书》特邀编委；河南省动物学会理事长；河南省濮阳黄河湿地生态系统野外科学观测研究站副站长。

代表性论文：

1. Wang L, Wang Y, Dong Z*, Chen G*, Sluy R, and Liu D. Integrative taxonomy unveils a new species of Dugesia (Platyhelminthes, Tricladida, Dugesiidae) from the southern portion of the Taihang Mountains in northern China,with the description of its complete mitogenome and an exploratory analysis of mitochondrial gene order as a taxonomic character. Integrative Zoology, 2021, 1-22.

2. Zimei Dong, Jinrui Huo, Ang Liang, Jinzi Chen, Guangwen Chen⁎, Dezeng Liu.Gamma-Secretase Inhibitor (DAPT), a potential therapeutic target drug,caused neurotoxicity in planarian regeneration by inhibiting Notch signaling pathway.Science of the Total Environment, 2021,781,146735.

3. Wang L, Chen J, Dong Z*, Chen G*, Sluy R, and Liu D. Two new species of Dugesia (Platyhelminthes, Tricladida, Dugesiidae) from the tropical monsoon forest in southern China. ZooKeys, 2021, 1059: 89-116.

4. Kang J, Chen J, Dong Z*, Chen G*, Liu D. The negative effect of the PI3K inhibitor 3-methyladenine on planarian regeneration via the autophagy signalling pathway. Ecotoxicology, 2021, 30(9): 1941-1948.

5. Wang L, Dong Z, Chen G*, Sluy R, Liu D. Integrative descriptions of two new species of Dugesia from Hainan Island, China (Platyhelminthes, Tricladida, Dugesiidae). ZooKeys, 2021, 1028: 1-28.

6. Yibo Yang, Peizheng Wang, Baijie Jin, Zimei Dong⁎, Guangwen Chen⁎, Dezeng Liu. Screening of Potential Key Transcripts Involved in Planarian Regeneration and Analysis of Its Regeneration Patterns by PacBio Long-Read Sequencing.Front Genet, 2020, 11: 580.

7. Fenxi Zhang, Zimei Dong⁎, Shuai Gao, Guangwen Chen⁎, Dezeng Liu.AT1R-Mediated  Apoptosis of Bone Marrow Mesenchymal Stem Cells Is Associated with mtROS  Production and mtDNA Reduction.Oxidative Medicine and Cellular Longevity,2019,4608165:1-9.

8. Baijie Jin, Jing Ren, Jinzi Chen, Zimei Dong*, Guangwen Chen*, Dezeng Liu. Autophagy‑related DjAtg1‑1 plays critical role in planarian regeneration by regulating proliferation and cell death. Cell and Tissue Research, 2022, doi.org/10.1007/s00441-022-03591-3.

9. Jing  Kang, Zimei Dong⁎, Hao Qin, Jing  Wang, Guangwen Chen⁎, Dezeng Liu.The regulation of rapamycin in planarian Dugesia japonica Ichikawa & Kawakatsu, 1964 regeneration according to TOR signaling pathway. Ecotoxicology and Environmental Safety, 2019,185:1-8.

10. Zimei Dong, Fangfang Cheng, Yibo Yang, Fenxi Zhang, Guangwen Chen⁎, Dezeng Liu.Expression and functional analysis of flotillins in Dugesia japonica.Experimental Cell Research,2019,374:76-84.

11. Qinghua Wang, Yingyu Liu, BaijieJin, Zimei Dong⁎, Guangwen Chen⁎, Dezeng Liu. Djmek is involved in planarian regeneration by regulation of cell proliferation and apoptosis.Biochem Biophys Res Commun, 2020, 532:355-361.

12. Qinghua Wang, Lijuan Xie, Yixuan Wang, Baijie Jin , Jing Ren , Zimei Dong *,Guangwen Chen*, Dezeng Liu. Djhsp70s, especially Djhsp70c, play a key role in planarian regeneration and tissue homeostasis by regulating cell proliferation and apoptosis. Gene, 2022 820 : 146215.

13. Yingyu Liu, JinziChen, ZimeiDong ⁎, Guangwen Chen ⁎, Dezeng Liu. Antioxidant responses and lipid peroxidation can be used as sensitive indicators for the heavymetals risk assessment of the Wei River: a casestudy of planarian Dugesia japonica. Biomarkers, 2021:26: 55-64.

14. Jing Kang, Zimei Dong⁎, Jing Wang, Guangwen Chen ⁎, Dezeng Liu. Autophagy-related djatg8 is required for remodeling in planarian Dugesia japonica. Biology Open,2019, 045013:8-12.

15. Zimei Dong, Gengbo Chu, Yingxu Sima, Guangwen Chen.Djhsp90s are crucial regulators during planarian regeneration and tissue homeostasis. Biochemical and Biophysical Research  Communications, 2018, 498:723-728.

16. Zimei Dong, Yibo Yang, Guangwen Chen, Dezeng Liu. Identification of runt family genes involved in planarian regeneration and tissue homeostasis. Gene Expression Patterns,2018,29:24-31.

17. Zimei Dong, Changying Shi, Gengbo Chu, Yanping Dong, Guangwen Chen, Dezeng Liu. Morphological changes of gonad and gene expression patterns during desexualization in Dugesia japonica (Platyhelminthes: Dugesiidae). Zoologia (Curitiba), 2018, 35:1-7.

18. Zimei Dong, Tong Yang, Yibo Yang, He Dou, Guangwen Chen. DjhnRNPA2/B1-like gene is required for planarian regeneration and tissue homeostasis.Gene,2017,633:9-16.

19. Zimei Dong, Yanqing Yuwen, Yingxu Sima, Yanping Dong, Huina Zhang, Guangwen Chen, Dezeng Liu. Photokinesis and Djopsin gene expression analysis during the regeneration of planarian eyes. Integrative Zoology, 2017:12:157-164.

20. Zimei Dong, Guangwen Chen, Hecai Zhang, Dezeng Liu.A new species of Polycelis (Platyhelminthes, Tricladida, Planariidae) from China. Acta Zoologica.2017, 63(3): 263-276.

21. Zimei Dong, Fangfang Cheng, Yanqing Yuwen, Jing Chen, Xiaoyan Li, He Dou, Haixia Zhang, Guangwen Chen, Dezeng Liu. Identification and expression analysis of a Spsb gene in planarian Dugesia japonica. Gene,2015,564:168-175.

22. Zimei Dong, Changying Shi, Haixia Zhang, He Dou, Fangfang Cheng, Guangwen Chen, Dezeng Liu. The characteristics of sox gene in Dugesia japonica. Gene, 2014,544:177-183.

23. Zimei Dong, Yanqing Yuwen, Qinghua Wang, Guangwen Chen, Dezeng Liu. Eight genes expression patterns during visual system regeneration in Dugesia japonica. Gene Expression Patterns,  2012,12:1-6.

专著教材： 

参编《动物学实验技术》,北京,科学出版社，2008年2月。

奖励：

1. 董自梅（4/6），基础教育生物学拔尖人才培养模式研究与实践。国家教学成果二等奖，2018。

2．董自梅（1/6）,人体寄生虫学教学内容、教学方法和教学手段的改革与实践。河南省高等教育教学成果一等奖，2016。