辛鹏洋个人简介

教育与研究经历：

2019.2-至 今 化学化工学院副教授

2015.7-2019.1 化学化工学院讲师

2012.9-2015.6 复 旦 大 学 获博士学位

2009.9-2012.6 获硕士学位

2005.9-2009.6 许 昌 学 院 获学士学位

研究领域与兴趣：

超分子化学、化学生物学。构建有机超分子体系模拟生物大分子的结构与功能，并进一步研究其在生物医药方面的潜在应用，在Acc. Chem. Res., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Green Chem.以及Chem. Commun.等国内外具有重要影响力的期刊上发表论文多篇。

近年来主持的主要科研项目:

1、国家自然科学基金-面上项目，2022，在研，主持

2、国家自然科学基金-联合基金，2020，在研，主持

3、河南省高等学校重点科研项目-基础研究专项，2021，在研，主持

4、国家自然科学基金面上项目培育项目，在研，主持

5、国家自然科学基金青年基金,结项，主持

6、河南省2016年科技发展计划-基础与前沿技术研究,结项，主持

代表性论文与专利：

1.Pengyang Xin,*Linqi Xu, Wenpei Dong, Linlin Mao, Jingjing Guo,* Jingjing Bi,Shouwei Zhang, Yan Pei, Chang-Po

Chen*,Synthetic K+ Channels Constructed by Rebuilding the Core Modulesof Natural K+ Channels in an Artificial

System.Angew. Chem. Int. Ed.,2023,e202217859.(Hot Paper,通讯作者，IF = 16.823)

2.Pengyang Xin,*Lingyu Zhao, Linlin Mao, Linqi Xu, Shuaimin Hou, Huiyuan Kong,Haodong Fang, Haofeng Zhu, Tao Jiang, Chang-Po Chen*,Effect of ChargeStatuson theIon Transport andAntimicrobialActivityofSynthetic Channels.Chem. Commun.,2020,DOI: 10.1039/D0CC05730D.(通讯作者，IF = 5.996)

3.Pengyang Xin,* Huiyuan Kong, Yonghui Sun, Lingyu Zhao, Haodong Fang, Haofeng Zhu, Tao Jiang, Jingjing Guo, Qian Zhang, Wenpei Dong, Chang-Po Chen*,Artificial K+Channels Formed by Pillararene-Cyclodextrin Hybrid Molecules: Tuning Cation Selectivity and Generating Membrane Potential,Angew. Chem. Int. Ed.,2019,58, 2779-2784.(通讯作者，IF = 12.102)

4.Pengyang Xin,* Si Tan, Yaodong Wang, Yonghui Sun, Yan Wang, Yuqing Xu andChang-Po Chen*,Functionalized hydrazide macrocycle ion channels showing pH-sensitive ion selectivities,Chem. Commun.,2017,53, 625-628.

(通讯作者，IF = 6.319)

5.Pengyang Xin,* Si Tan, Yonghui Sun, Qiaojv Ren, Wenpei Dong, Jingjing Guo, Tao Jiang and Chang-Po Chen,*

One-pot formation of hydrazide macrocycles with modified cavities: an example of pH-sensitive unimolecular cation channels,Chem. Commun.,2017,53, 5322-5325.(通讯作者，IF = 6.319)

6.Pengyang Xin,* Yonghui Sun, Huiyuan Kong, Yaodong Wang, Si Tan, Jingjing Guo, Tao Jiang, Wenpei Dong* and Chang-Po Chen*,A unimolecular channel formed by dual helical peptide modified pillar[5]arene: correlating transmembrane transport properties with antimicrobial activity and haemolytic toxicity,Chem. Commun.,2017,53, 11492-11495.(通讯作者，IF = 6.319)

7.Min Zhang, Ping-Ping Zhu ,Pengyang Xin, Wen Si, Zhan-Ting Li, and Jun-Li Hou*,Synthetic Channel Specifically Inserts into the Lipid Bilayer of GramPositive Bacteria but not that of Mammalian Erythrocytes,Angew. Chem. Int. Ed.,2017,56, 2999-3003.(IF = 11.994)

8.Lingjun Li* , Qianqian Li, Shengqiang Ding,Pengyang Xin, Yuqin Zhang, Shenlong Huang and Guisheng Zhang*,ADP-ribosyl-N3: A Versatile Precursor for Divergent Syntheses of ADP-ribosylated Compounds,Molecules,2017,22, 1346.(IF = 2.861)

9.Pengyang Xin,PingpingZhu, Pei Su, Jun-Li Hou* and Zhan-Ting Li*,Hydrogen-Bonded Helical Hydrazide Oligomer and Polymer That Mimic the Ion Transport of Gramicidin A,J. Am. Chem. Soc.,2014,136, 13078-13081.

(第一作者,IF = 12.113)

10.Pengyang Xin, Liang Zhang, Pei Su, Jun-Li Hou* and Zhan-Ting Li*,Hydrazide macrocycles as effective transmembrane channels for ammonium.Chem. Commun.,2015, 47,11140-11142.(第一作者，IF = 6.834)

11.Peng-Yang Xin, Hong-Ying Niu, Gui-Rong Qu* Rui-Fang Ding, Hai-Ming Guo*,Nickel catalyzed alkylation of N-aromatic heterocycles with Grignard reagents through direct C–H bond functionalization.Chem. Commun.,2012,48, 6717- 6719.(第一作者，IF = 6.834)

12.Gui-Rong Qu,*Peng-Yang Xin,Hong-Ying Niu, Dong-Chao Wang, Rui-Fang Ding, Hai-Ming Guo*,Nickel-catalyzed sp²C–H bonds arylation of N-aromatic heterocycles with Grignard reagents at room temperature.Chem. Commun.,2011,47,11140-11142.(除导师外第一作者，IF = 6.834)

13.Hai-Ming Guo,*Peng-Yang Xin, Hong-Ying Niu, Gui-Rong Qu*,Microwave irradiated C⁶-functionalization of 6-chloropurine nucleosides with various mild nucleophiles under solvent-free conditions.Green Chem.,2010,12, 2131-2134.(除导师外第一作者，IF = 8.02)

14.Gui-Rong Qu,*Peng-Yang Xin, Hong-Ying Niu,Hai-Ming Guo,*Microwave promoted palladium-catalyzed Suzuki-Miyaura cross-coupling reactions of 6-chloropurines with sodium tetraarylborate in water.Tetrahedron,2011,67,9099- 9103.(除导师外第一作者，IF = 2.803)

15.Yingtang Zhang,*Pengyang Xin,*Qiufeng Yao,Electrochemical performance of LiFePO4/C synthesized by sol-gel method as cathode for aqueous lithium ion batteries.J. Alloy. Compd.,2018,74,404-408.(通讯作者，IF = 3.779)

16.Wen Si,Pengyang Xin,Zhan-Ting Li, Jun-Li Hou,*Tubular UnimolecularArtificial Transmembrane Channels:Construction Strategies and Transport Activities.Acc. Chem. Res.,2015,48,1612-1619.(IF = 22.323)

17.Qian Zhang,*Chun-Hang Zhang,Jun-Hui Yang,Peng-Yang Xin,Xiao-Peng Xuan,Jian-Ge Wang,Na-Na Ma,Hai-MingGuo andGui-Rong Qu,A four-unit [c2]daisy chain connected by hydrogen bonds.Chem. Commun.,2015,51, 15253-15256.(IF = 6.834)

18.Yu-Qin Jiang, Kai Wu, Qian Zhang, * Ke-Qing Li, Yan-Yan Li,Peng-Yang Xin, Wei-Wei Zhang and Hai-Ming Guo*,A dual-responsive hyperbranched supramolecular polymer constructed by cooperative host–guest recognition and hydrogen-bond interactions.Chem. Commun.,2018,54, 13821-13824.(IF = 6.834)

19.辛鹏洋，牛红英，渠桂荣，杨西宁，郭海明,*四芳基硼钠的简便合成.合成化学，2011,19,671-672.

20.祝平平，辛鹏洋，侯军利*，黎占亭*,乙酰胆碱经人工通道的跨膜输送.Chin. J. Org. Chem.,2015,35, 1994-1998.

21.祝平平，辛鹏洋，侯军利*，黎占亭*,间苯二甲酸自组装形成的人工跨膜离子通道.中国科学:化学,2015,45,624-628.

22.郭海明*,李璞,辛鹏洋,王东超,牛红英,渠桂荣*,微波促进的6-位磷功能化的非环嘌呤核苷类似物的合成.中国科学:化学,2010,40, 963-966.