个人简介:
毛国江,博士,副教授,硕士生导师。
E-mail:maoguojiang@htu.edu.cn
教育经历:
2003年9月-2007年6月 湖南大学化学化工学院,化学工程与工艺专业,工学学士;
2007年9月-2009年6月 湖南大学化学化工学院,有机化学专业,理学硕士;
2009年9月-2014年6月 湖南大学化学化工学院,分析化学专业,理学博士。
工作经历:
2014年7月-2022年3月 化学化工学院,讲师,硕士生导师。
2022年4月-至今化学化工学院,副教授,硕士生导师。
研究领域与兴趣:
1、荧光分子探针的设计合成
2、荧光成像分析
3、生物分析与生物传感
近年来主持的主要科研项目:
1、2023年河南省高等学校重点科研项目计划
2、2020年河南省科技攻关项目
3、2015年国家自然科学基金项目
代表性论文:
(1)Jun-Tao Chen; Si-Si Chen; Zhi-Qing Wang; Guo Yu;Guo-Jiang Mao*; Junjie Fei; Chun-Yan Li*; Near-Infrared Fluorescent Nanoprobes for Adenosine Triphosphate-Guided Imaging in Cancer and Fatty Liver Mice,Analytical Chemistry,2023, 95(3): 2119-2127.
(2)Ling Yan; Qing-Song Gu; Wen-Li Jiang; Min Tan; Zhi-Ke Tan;Guo-Jiang Mao*; Fen Xu; Chun-Yan Li*; Near-infrared fluorescent probe with large stokes shift for imaging of hydrogen sulfide in tumor-bearing mice,Analytical Chemistry,2022, 94(14): 5514-5520.
(3)Wen-Xin Wang; Wen-Li Jiang;Guo-Jiang Mao*; Zhi-Ke Tan; Min Tan; Chun-Yan Li*; A novel near-infrared theranostic probe for accurate cancer chemotherapy in vivo by a dual activation strategy,Chemical Communications,2021, 57: 13768-13771.
(4)Guo-Jiang Mao*; Zhen-Zhen Liang; Jingjing Bi; Hua Zhang*; Hong-Min Meng; Li Su; Yi-Jun Gong; Suling Feng; Guisheng Zhang*; A near-infrared fluorescent probe based on photostable Si-rhodamine for imaging hypochlorous acid during lysosome-involved inflammatory response,Analytica Chimica Acta,2019, 1048: 143-153.
(5)Guo-Jiang Mao*; Guang-Qi Gao; Zhen-Zhen Liang; Ying-Ying Wang; Li Su; Zhuo-Xi Wang; Hua Zhang*; Qiu-Juan Ma; Guisheng Zhang*; A mitochondria-targetable two-photon fluorescent probe with a far-red to near-infrared emission for sensing hypochlorite in biosystems,Analytica Chimica Acta,2019, 1081: 184-192.
(6)Guo-Jiang Mao*; Zhen-Zhen Liang; Guang-Qi Gao; Ying-Ying Wang; Xin-Yu Guo; Li Su; Hua Zhang*; Qiu-Juan Ma; Guisheng Zhang*; A photostable Si-rhodamine-based near-infrared fluorescent probe for monitoring lysosomal pH during heat stroke,Analytica Chimica Acta,2019, 1092: 117-125.
(7)Guo-Jiang Mao*; Guang-Qi Gao; Wen-Pei Dong; Qian-Qian Wang; Ying-Ying Wang; Yao Li; Li Su; Guisheng Zhang*; A two-photon excited near-infrared fluorescent probe for imaging peroxynitrite during drug-induced hepatotoxicity and its remediation,Talanta,2021, 221: 121607.
(8)Di Zhao; Hongmin Meng*; Ming-Qing Shi; Na Li;Guo-Jiang Mao*; Two-photon excited fluorescent silica nanoparticles loaded with iron(II) as a probe for determination and imaging of hydrogen peroxide in living cells,Microchimica Acta,2019, 186: 805.
(9)Yi-Jun Gong*; Meng-Ke Lv; Ming-Lu Zhang; Zhen-Zhen Kong;Guo-Jiang Mao*; A novel two-photon fluorescent probe with long-wavelength emission for monitoring HClO in living cells and tissues,Talanta,2019, 192: 128-134.
(10)Guo-Jiang Mao*; Ying-Ying Wang; Wen-Pei Dong; Hong-Min Meng; Qian-Qian Wang; Xiao-Feng Luo; Yao Li; Guisheng Zhang*; A lysosome-targetable two-photon excited near-infrared fluorescent probe for visualizing hypochlorous acid-involved arthritis and its treatment,Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,2021, 249: 119326.
(11)Qiujuan Ma*; Junhong Xu;Guojiang Mao*; Xiaoyu Guo; Beibei Liang; Yu Bai; Chunyan Wang; A highly sensitive and selective fluorescent probe for nitroxyl based on a naphthalene derivative,Analytical Methods,2019, 11: 832-843.
(12)Qian‑Qian Wang*; Ying‑Ying Wang; Yao Li; Shu‑Yu Zhang; Xin‑Yu Guo; Wen‑Ke Zha; Wen‑Jun Li;Guo-Jiang Mao*; A lysosome‑targetable fluorescent probe based on HClO‑mediated cyclization reaction for imaging of hypochlorous acid,Analytical Sciences,2022, 38: 175-182.
(13)Jingguo Sun; Junhong Xu; Qiujuan Ma*;Guojiang Mao*; Nannan Zhu; Meiju Tian; Linke Li; Shuzhen Liu; A highly selective fluorescent probe for hypochlorous acid in living cells based on a naphthalene derivative,International Journal of Analytical Chemistry,2022, 2022: 7649230.
(14)Guo-Jiang Mao, Tian-Tian Wei, Xu-Xiang Wang, Shuang-Yan Huan, Dan-Qing Lu, Jing Zhang, Xiao-Bing Zhang*, Weihong Tan*, Guo-Li Shen, and Ru-Qin Yu. High-sensitivity naphthalene-based two-photon fluorescent probe suitable for direct bioimaging of H2S in living cells.Analytical Chemistry,2013, 85(16):7875-7881.
(15)Guo-Jiang Mao, Xiao-Bing Zhang*, Xue-Lin Shi, Hong-Wen Liu, Yong-Xiang Wu, Li-Yi Zhou, Weihong Tan*, Ru-Qin Yu. A highly sensitive and reductant-resistant fluorescent probe for nitroxyl in aqueous solution and serum.Chemical Communications,2014, 50: 5790-5792.
(16)Hong-Min Meng, Xiao-Bing Zhang*, Chan Yang, Hailan Kuai,Guo-Jiang Mao, Liang Gong, Wenhan Zhang, Suling Feng, Junbiao Chang*, Efficient Two-Photon Fluorescence Nanoprobe for Turn-On Detection and Imaging of Ascorbic Acid in Living Cells and Tissues,Analytical Chemistry,2016, 88(11): 6057-6063.
授权发明专利:
(1)毛国江;高广琦;王盈盈;梁珍珍;一种线粒体靶向的次氯酸根双光子荧光探针及其制备方法和应用,2022-1-4,中国,ZL 201910436820.8